Apidra duration of action

APIDRA - GP2U

The glucose lowering activities of APIDRA and of regular human insulin are equipotent when administered by the intravenous route. Studies in healthy volunteers and patients with diabetes demonstrated that APIDRA has a more rapid onset of action and a shorter duration of activity than regular human insulin when given subcutaneously.

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November 9th,2019

APIDRA - GP2U

The glucose lowering activities of APIDRA and of regular human insulin are equipotent when administered by the intravenous route. Studies in healthy volunteers and patients with diabetes demonstrated that APIDRA has a more rapid onset of action and a shorter duration of activity than regular human insulin when given subcutaneously.

November 9th,2019

Shortage of Apidra (insulin glulisine) cartridges

equivalent. As these insulins have a slower onset and a longer duration of action than Apidra, this must be done under the direct supervision of a healthcare professional with more frequent monitoring of blood glucose levels and adjusted dose as required. • Patients for whom vials and syringes are an acceptable alternative to a pen device may be

November 9th,2019

Typical Insulin Profiles

Manufacturer Device Taken Onset Peak Duration Typical activity profiles Rapid-acting analogue insulins Insulin Aspart NovoRapid® Novo Nordisk Vial, Flexpen, cartridge Just before, with or just after food 10-20 mins 1-3 hrs 2-5 hrs Insulin Lispro Humalog® Lilly Vial, Kwikpen, cartridge Insulin Glulisine Apidra® Sanofi-Aventis

November 9th,2019

Average Insulin Action Time

Average Insulin Action Time When calculating a correction dose of insulin, please consider the action times of the insulins you are using and consider correcting to 10 mmol/L if only 2 hours after eating. Insulin Average insulin action Rapid-acting Onset 10 to 20 min, Peak 1 to 3 h, Duration 3 to 5 h •Admelog®, Humalog® •Apidra ...

November 9th,2019

HIGHLIGHTS OF PRESCRIBING INFORMATION —————————— …

APIDRA ® (insulin glulisine ... The risk of hypoglycemia after an injection is related to the duration of action of the insulin and, in general, is highest when the glucose lowering effect of the insulin is maximal. The timing of hypoglycemia usually reflects the time-action profile of the administered insulin formulation. As with all insulin preparations, the glucose lowering effect time course of APIDRA may …

November 9th,2019

Apidra (insulin glulisine)

APIDRA has a more rapid onset of action and a shorter duration of action than regular human insulin. APIDRA should normally be used in regimens that include a longer-acting insulin or basal insulin analogue to maintain adequate glucose control (see DOSAGE AND ADMINISTRATION). APIDRA can be used with oral hypoglycemic agents.

November 9th,2019

CHMP ASSESSMENT REPORT Apidra

Insulin glusilin (Apidra) displays a time-concentration and time-action profile with a more rapid onset, earlier peak effect in lowering blood glucose levels, and a shorter duration of action than the short-acting insulin preparation of regular insulin. However, when administered intravenously, insulin

November 9th,2019

How to Switch Between Insulin Products - SCCG

Apidra), or insulin lispro (Humalog) to regular human insulin (Humulin, Novolin) • Convert unit-per-unit. 3,7,8,9 • Rapid-acting insulin analogs have a faster onset of action and a shorter duration of action than human regular insulin. Give regular insulin about 30 minutes before meals. See Comparison of Insulins for specifics of meal ...

November 9th,2019

HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights …

APIDRA is a recombinant insulin analog that is equipotent to human insulin (i.e. one unit of APIDRA has the same glucose-lowering effect as one unit of regular human insulin) when given intravenously. When given subcutaneously, APIDRA has a more rapid onset of action and a shorter duration of action than regular human insulin.

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